Preclinical and 7T publications 2015

• Erlandsson L, Nääv Å, Hennessy A, Vaiman D, Gram M, Åkerström B, Hansson SR. Inventory of Novel Animal Models Addressing Etiology of Preeclampsia in the Development of New Therapeutic/Intervention Opportunities. Am J Reprod Immunol. 2016 Mar;75(3):402-10. doi: 10.1111/aji.12460. Epub 2015 Dec 18.
• Ahlstedt J., Tran T.A., Strand S-E, Gram M., Åkerström B. Human Anti-Oxidation Protein A1M—A Potential Kidney Protection Agent in Peptide Receptor Radionuclide Therapy. Int. J. Mol. Sci. 18 December 2015, 16(12), 30309-30320. doi:10.3390/ijms161226234.
• Sjölund J, Szczepankiewicz F, Nilsson M, Topgaard D, Westin CF, Knutsson H. Constrained optimization of gradient waveforms for generalized diffusion encoding. J Magn Reson. 2015 261:157-68.
• Kjellman P, Fredriksson S, Kjellman C, Sven-Erik Strand S-E, in ‘t Zandt R. Size-dependent lymphatic uptake of nanoscale-tailored particles as tumor mass increases. Future Science OA. 2015. [Epub ahead of print]
• Ahlstedt J, Tran TA, Strand F, Holmqvist B, Strand S-E, Gram M, Åkerström B. Biodistribution and pharmacokinetics of recombinant α1-microglobulin and its potential use in radioprotection of kidneys. Am J Nucl Med Mol Imaging 2015;5(4):333-347, www.ajnmmi.us /ISSN:2160-8407/ajnmmi0007393. Published July 1, 2015.
• Degerman E, In ‘t Zandt R, Pålbrink A, Magnusson M. Vasopressin induces endolymphatic hydrops in mouse inner ear, as evaluated with repeated 9.4 T MRI. Hear Res. 2015 Jun 3. pii: S0378-5955(15)00116-1. [Epub ahead of print]
• Manouchehrian O, Arnér K, Deierborg T, Taylor L. Who let the dogs out?: detrimental role of Galectin-3 in hypoperfusion-induced retinal degeneration. J Neuroinflammation. 2015 12:92.
• Nääv Å, Erlandsson L, Axelsson J, Larsson I, Johansson M, Wester-Rosenlöf L, Mörgelin M, Casslén V, Gram M, Åkerström B, Hansson SR. A1M Ameliorates Preeclampsia-Like Symptoms in Placenta and Kidney Induced by Cell-Free Fetal Hemoglobin in Rabbit. PLoS One. 2015 May 8;10(5):e0125499. doi: 10.1371/journal.pone.0125499. eCollection 2015.
• Braekeveldt N, Wigerup C, Gisselsson D, Mohlin S, Merselius M, Beckman S, Jonson T, Börjesson A, Backman T, Tadeo I, Berbegall AP, Ora I, Navarro S, Noguera R, Påhlman S, Bexell D. Neuroblastoma Patient-Derived Orthotopic Xenografts Retain Metastatic Patterns and Geno- and Phenotypes of Patient Tumours. Int J Cancer. 2015 Mar 1;136(5):E252-61. doi: 10.1002/ijc.29217. Epub 2014 Oct 7
• Bosemark P, Perdikouri C, Pelkonen M, Isaksson H, Tägil M. The masquelet induced membrane technique with BMP and a synthetic scaffold can heal a rat femoral critical size defect. J Orthop Res. 2015 Apr;33(4):488-95.]
• Timmermand OV, Tran TA, Strand SE, Axelsson J. Intratherapeutic biokinetic measurements, dosimetry parameter estimates, and monitoring of treatment efficacy using cerenkov luminescence imaging in preclinical radionuclide therapy. J Nucl Med. 2015 Mar;56(3):444-9. Epub 2015 Feb 5.
• Vilhelmsson-Timmermand O, Santos E, Thorek D.L.J., Evans-Axelsson S, Bjartell A, Lilja H, Larson S.M., Strand S-Ea, Tran T.A., Ulmert D. Radiolabeled antibodies in prostate cancer: A case study showing the effect of host immunity on antibody bio-distribution. Nuclear Medicine and Biology. In press. [Epub ahead of print]
• Hansson SR, Nääv Å, Erlandsson L. Oxidative stress in preeclampsia and the role of free fetal hemoglobin. Front Physiol. 2015 Jan 13;5:516. doi: 10.3389/fphys.2014.00516. eCollection 2014.

Clinical publications 2015

• Oldenburg J, Zimmermann R, Katsarou O, Theodossiades G, Zanon E, Niemann B, Kellermann E & Lundin B. Controlled, cross-sectional MRI evaluation of joint status in severe haemophilia A patients treated with prophylaxis vs. on demand. 2015 I : Haemophilia. 21, 2, s. 171-179.
• Macfarlane MD, Jakabek D, Walterfang M, Vestberg S, Velakoulis D, Wilkes FA, Nilsson C, van Westen D, Looi JCL & Santillo A. Striatal Atrophy in the Behavioural Variant of Frontotemporal Dementia: Correlation with Diagnosis, Negative Symptoms and Disease Severity. 2015 I : PLoS ONE. 10, 6, e0129692.
• Roll M, Söderström P, Mannfolk P, Shtyrov Y, Johansson M, van Westen D & Horne M. Word tones cueing morphosyntactic structure: Neuroanatomical substrates and activation time-course assessed by EEG and fMRI. Brain and Language. 150, s. 14-21.2015.
• Sjölund J, Szczepankiewicz F, Nilsson M, Topgaard D, Westin C-F, Knutsson H. Constrained optimization of gradient waveforms for generalized diffusion encoding. J Magn Reson, 2015, 261:157–168.
• Nilsson M, Szczepankiewicz F, Hansson O, van Westen D. Extrapolation-based references improve motion correction of high b-value DWI data: Application in Parkinson’s disease dementia. PLoS ONE, 2015, 10(11): e0141825.
• Surova Y, Nilsson M, Lätt J, Lampinen B, Lindberg O, Hall S, Widner H, Nilsson C, van Westen D, Hansson O. Disease-specific structural changes in thalamus and dentatorubrothalamic tract in progressive supranuclear palsy. Neuroradiology. 2015 Nov;57(11):1079-91. doi: 10.1007/s00234-015-1563-z. Epub 2015 Aug 8.
• Bibic A, Knutsson L, Schmidt A, Henningsson E, Månsson S, Abul-Kasim K, Åkeson J, Gunther M, Ståhlberg F, Wirestam R. Measurement of vascular water transport in human subjects using time-resolved pulsed arterial spin labelling. NMR Biomed. 2015 Aug;28(8):1059-68. doi: 10.1002/nbm.3344. Epub 2015 Jul 5.
• Szczepankiewicz F, Lasič S, van Westen D, Sundgren PC, Englund E, Westin CF, Ståhlberg F, Lätt J, Topgaard D, Nilsson M. Quantification of microscopic diffusion anisotropy disentangles effects of orientation dispersion from microstructure: applications in healthy volunteers and in brain tumors. Neuroimage. 2015 Jan 1;104:241-52. doi: 10.1016/j.neuroimage.2014.09.057. Epub 2014 Oct 2.
• Nilsson A, Revstedt J, Heiberg E, Ståhlberg F, Bloch KM. Volumetric velocity measurements in restricted geometries using spiral sampling: a phantom study. MAGMA. 2015 Apr;28(2):103-18. doi: 10.1007/s10334-014-0449-0. Epub 2014 May 18.
• Knutsson L, Lindgren E, Ahlgren A, van Osch MJ, Markenroth Bloch K, Surova Y, Ståhlberg F, van Westen D, Wirestam R. Reduction of arterial partial volume effects for improved absolute quantification of DSC-MRI perfusion estimates: comparison between tail scaling and prebolus administration. J Magn Reson Imaging. 2015 Apr;41(4):903-8. doi: 10.1002/jmri.24621. Epub 2014 Mar 24.
• Carlsson M, Jögi J, Bloch KM, Hedén B, Ekelund U, Ståhlberg F, Arheden H. Submaximal adenosine-induced coronary hyperaemia with 12 h caffeine abstinence: implications for clinical adenosine perfusion imaging tests. Clin Physiol Funct Imaging. 2015 Jan;35(1):49-56. doi: 10.1111/cpf.12125. Epub 2014 Jan 12.
• Jablonowski R, Engblom H, Kanski M, Nordlund D, Koul S, van der Pals J, Englund E, Heiberg E, Erlinge D, Carlsson M, Arheden H. Contrast-Enhanced CMR Overestimates Early Myocardial Infarct Size: Mechanistic Insights Using ECV Measurements on Day 1 and Day 7. JACC Cardiovasc Imaging. 2015 Dec;8(12):1379-1389. doi: 10.1016/j.jcmg.2015.08.015.
• Kanski M, Arvidsson PM, Töger J, Borgquist R, Heiberg E, Carlsson M, Arheden H. Left ventricular fluid kinetic energy time curves in heart failure from cardiovascular magnetic resonance 4D flow data. J Cardiovasc Magn Reson. 2015 Dec 20;17:111. doi: 10.1186/s12968-015-0211-4.
• Xanthis CG, Bidhult S, Kantasis G, Heiberg E, Arheden H, Aletras AH. Parallel simulations for QUAntifying RElaxation magnetic resonance constants (SQUAREMR): an example towards accurate MOLLI T1 measurements. J Cardiovasc Magn Reson. 2015 Nov 26;17:104. doi: 10.1186/s12968-015-0206-1.
• Steding-Ehrenborg K, Boushel RC, Calbet JA, Åkeson P, Mortensen SP. Left ventricular atrioventricular plane displacement is preserved with lifelong endurance training and is the main determinant of maximal cardiac output. J Physiol. 2015 Dec 1;593(23):5157-66. doi: 10.1113/JP271621. Epub 2015 Nov 18.
• Wiiala J, Hedström E, Kraen M, Magnusson M, Arheden H, Engblom H. Diagnostic performance of the Selvester QRS scoring system in relation to clinical ECG assessment of patients with lateral myocardial infarction using cardiac magnetic resonance as reference standard. J Electrocardiol. 2015 Sep-Oct;48(5):750-7. doi: 10.1016/j.jelectrocard.2015.07.009. Epub 2015 Jul 9.
• Åkerlund S, Wieslander B, Turesson M, Nijveldt R, Klem I, Almer J, Engblom H, Wagner GS, Atwater BD, Ugander M. Specificity for each of the 46 criteria of the Selvester QRS score for electrocardiographic myocardial scar sizing in left bundle branch block. J Electrocardiol. 2015 Sep-Oct;48(5):769-76. doi: 10.1016/j.jelectrocard.2015.07.018. Epub 2015 Jul 21.
• Tufvesson J, Hedström E, Steding-Ehrenborg K, Carlsson M, Arheden H, Heiberg E. Validation and Development of a New Automatic Algorithm for Time-Resolved Segmentation of the Left Ventricle in Magnetic Resonance Imaging. Biomed Res Int. 2015;2015:970357. doi: 10.1155/2015/970357. Epub 2015 Jun 21.
• Kanski M, Töger J, Steding-Ehrenborg K, Xanthis C, Bloch KM, Heiberg E, Carlsson M, Arheden H. Whole-heart four-dimensional flow can be acquired with preserved quality without respiratory gating, facilitating clinical use: a head-to-head comparison. BMC Med Imaging. 2015 Jun 18;15:20. doi: 10.1186/s12880-015-0061-4.
• Jablonowski R, Fernlund E, Aletras AH, Engblom H, Heiberg E, Liuba P, Arheden H, Carlsson M. Regional Stress-Induced Ischemia in Non-fibrotic Hypertrophied Myocardium in Young HCM Patients. Pediatr Cardiol. 2015 Dec;36(8):1662-9. doi: 10.1007/s00246-015-1214-5. Epub 2015 Jun 12.
• Atar D, Arheden H, Berdeaux A, Bonnet JL, Carlsson M, Clemmensen P, Cuvier V, Danchin N, Dubois-Randé JL, Engblom H, Erlinge D, Firat H, Halvorsen S, Hansen HS, Hauke W, Heiberg E, Koul S, Larsen AI, Le Corvoisier P, Nordrehaug JE, Paganelli F, Pruss RM, Rousseau H, Schaller S, Sonou G, Tuseth V, Veys J, Vicaut E, Jensen SE. Effect of intravenous TRO40303 as an adjunct to primary percutaneous coronary intervention for acute ST-elevation myocardial infarction: MITOCARE study results. Eur Heart J. 2015 Jan 7;36(2):112-9. doi: 10.1093/eurheartj/ehu331. Epub 2014 Sep 1.